Dr. Dinh-Truong Nguyen
Professor Tan Tao University, Vietnam.
Biography:
Abstract:
Breast cancer known as the heterogeneous disease and frequently prolonged for several year with potential risks in metastasizing to other organs in the body remains one of the leading causes of cancer related death in women worldwide that requires a complex combination of solutions involving interference in the regulation of the gene expression and other complicated clinical treatments. ASMT is a key determinant of the levels of released melatonin. Though melatonin has been shown to exhibit anti-cancer activity and prevents endocrine resistance in breast cancer, the role of ASMT in breast cancer progression remains unclear. The necessity to build a prognosis model to predict its spread to other sites is extremely urgent. So herein, we conducted this research to seeking the gene signature related to the metastasis of Breast cancer to Lung to improve the accuracy of current diagnostic methods at the earliest stages, and importantly further investigate the significance of ASMT expression in human breast cancer and its relationship to survival outcomes in order to increase the survival rate for patients.